PANTOPRAZOLE AND 24-HOUR INTRAGASTRIC ACIDITY
نویسندگان
چکیده
منابع مشابه
24 hour intragastric acidity during maintenance treatment with ranitidine.
We acknowledge the valuable support rendered by the Smith, Kline and French medical department.
متن کاملEffect of daily oral omeprazole on 24 hour intragastric acidity.
Twenty four hour intragastric acidity was measured in nine patients with duodenal ulcer before and after one week of treatment with oral omeprazole 30 mg daily, a drug that inhibits gastric secretion by inhibition of parietal cell H+K+ adenosinetriphosphatase (ATPase). Omeprazole virtually eliminated intragastric acidity in all patients: the median 24 hour intragastric pH rose from 1.4 to 5.3 a...
متن کاملSufotidine 600 mg bd virtually eliminates 24 hour intragastric acidity in duodenal ulcer subjects.
In a double blind study, 24 hour intragastric acidity and 24 hour plasma gastrin concentrations were measured simultaneously in seven duodenal ulcer subjects on the fifth day of receiving either sufotidine 600 mg bd or placebo. Compared with placebo, during treatment with sufotidine 600 mg bd the median integrated 24 hour intragastric acidity was decreased by 95% (range 74% to 99%) from 1000 to...
متن کاملEvaluation of pirenzepine on gastric acidity in healthy volunteers using ambulatory 24 hour intragastric pH-monitoring.
The effect of pirenzepine on 24 hour intragastric acidity was studied in 10 healthy volunteers using ambulatory 24 hour intragastric pH-monitoring in a double blind crossover study. Tests were performed on the seventh day of ingestion of either placebo, 75 mg pirenzepine or 150 mg pirenzepine per day. The drugs were given at two doses at 8.30 am and 8.30 pm. Mean nocturnal hydrogen ion activity...
متن کاملOptimal dose of oral omeprazole for maximal 24 hour decrease of intragastric acidity.
In a series of 59 experiments in nine duodenal ulcer patients, 24 hour intragastric acidity was measured before, during, and after treatment with daily oral omeprazole. Omeprazole 10, 20, and 30 mg/day for one week caused a 37, 90, and 97% decrease of 24 hour intragastric acidity, respectively. No further decrease of acidity was observed when the dose of omeprazole was doubled to 60 mg/day, or ...
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ژورنال
عنوان ژورنال: Alimentary Pharmacology & Therapeutics
سال: 2007
ISSN: 0269-2813,1365-2036
DOI: 10.1111/j.1365-2036.1993.tb00077.x